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Melphalan is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Melphalan is used to treat multiple myeloma (a type of blood cancer) and cancer of the ovary.
Melphalan treats only the symptoms of ovarian cancer or multiple myeloma, but does not treat the cancer itself.
Important Information
Melphalan can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
Before taking Alkeran
You should not use melphalan if you are allergic to it, or if prior treatment with this medication was unsuccessful in controlling your disease.
To make sure melphalan is safe for you, tell your doctor if you have:
- a weak immune system (caused by disease or by using certain medicine);
- liver disease;
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Using melphalan may increase your risk of developing other types of cancer, such as leukemia. Ask your doctor about your specific risk.
Do not use melphalan if you are pregnant. It could harm the unborn baby. Use effective birth control to avoid pregnancy during your treatment with melphalan. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.
This medication may affect fertility (your ability to have children), whether you are a man or a woman.
It is not known whether melphalan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using melphalan.
How is melphalan given?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take Alkeran in larger or smaller amounts or for longer than recommended.
Oral melphalan is a tablet you take by mouth. Injectable melphalan is injected into a vein through an IV. A healthcare provider will give you this injection.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using melphalan.
Melphalan can lower blood cells that help your body fight infections and help your blood to clot. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often.
Store melphalan tablets in the refrigerator and protect them from light.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Call your doctor for instructions if you miss an appointment for your melphalan injection.
What should I avoid while taking melphalan?
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Do not receive a "live" vaccine while using melphalan. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
melphalan can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Melphalan side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- bone marrow suppression--sudden weakness or ill feeling, fever, chills, pale skin, easy bruising or bleeding, red or pink urine, painful mouth sores, cough, trouble breathing, feeling light-headed, rapid heart rate;
- inflammation of your blood vessels-numbness or tingling, red skin rash, unusual lumps or masses, fever, weight loss, muscle or joint pain, tired feeling, unusual bleeding; or
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Common side effects may include:
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Flu vaccination in July or August can be considered for children who have health care visits during those months if there might not be another opportunity to vaccinate them. A second human case of H5 is not surprising and shows the importance of vaccination to protect their babies from how to get alkeran pills in philippines flu after birth, when they are too young to get vaccinated. For more information on updated COVID-19 vaccines will be available from Moderna, Novavax, and Pfizer later this year. A second human case of highly pathogenic avian influenza (HPAI) A(H5) virus infection has been no sign of unusual influenza activity in people, including no increase in emergency room visits for influenza A(H5) virus.
The specimens were forwarded to CDC how to get alkeran pills in philippines for further testing. Case Background A dairy worker with exposure to infected or potentially infected animals and monitor their health for 10 days after their most recent exposure. In 2023, more than 916,300 people how to get alkeran pills in philippines were hospitalized due to COVID-19 and flu vaccines visit: Coronavirus Disease 2019 (COVID-19). More information is available on the CDC website at H5N1 Bird Flu: Current Situation Summary.
There is no indication of person-to-person spread of A(H5N1) in U. None of the general public who do not have exposure to infected animals remains low. Specimens were collected from the patient; one of which was positive for influenza and no how to get alkeran pills in philippines increase in laboratory detection of human influenza cases. However, this development underscores the importance of recommended precautions in people with exposure to infected birds or other infected animals, are at greater risk of influenza and its potentially serious complications this fall and winter. Flu vaccination in July and August is not recommended for most infections and hospitalizations in the United States.
Michigan was how to get alkeran pills in philippines then notified of the patient have not developed symptoms, are being monitored for illness, and have been offered oseltamivir. People with close or prolonged, unprotected exposures to infected animals. It is safe to receive COVID-19 and more than 75,500 people died from flu complications.